11 Best Supplements for Stomach Health

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Best Supplements for Stomach Health (1)

If you’re like most people, you probably don’t think about your stomach until there’s a problem. And by then, it’s often too late.

Your stomach is one of the most important parts of your body, and it deserves some attention – especially if you’re not feeling well.

In this article, we’ll discuss the best supplements for stomach health. We’ll talk about what to look for in a good supplement, and we’ll give you our top picks. You may want to see our post about supplements for gut inflammation too.

So whether you’re dealing with occasional indigestion or more serious gut health problems, read on for some helpful advice!

If you want more helpful info on supplements – including risks and general FDA guidelines – please see our “Supplements and Vitamins – Ultimate Beginner’s Guide”.

How We Rank and Review – 8 Criteria

1 – Price: What’s the price of the supplement? What’s the cost per serving?

  • At Eating Enlightenment we value quality over price. However, all else being equal, then price comes into consideration. 

2 – Reviews: How many reviews for each product? What’s the average rating? How many third party reviews?

  • We strongly believe in third party reviews. Many supplement companies list positive reviews on their website, but third party reviews include negative comments. We always go with third party reviews.

3 – Reputation: How reputable is the brand behind the supplement? How long has the brand been around? What’s their mission? 

  • We believe that a company’s intention is highly important and should be one of your top purchasing decision factors.

4 – Taste / Absorption:  What’s the taste? How quickly does your body absorb the supplement? Do reviews mention any negative side effects like an upset stomach?

5 – Perceived Therapeutic Effect:  What beneficial effects or feelings does this supplement promote?

6 – Food Allergens:  Does the company provide allergen info?

7 – Science / Certifications: Does the company list transparent scientific studies on their website? Do third party certifications test the company’s supplement for quality control? How many certifications does the company have?

8 – Pros/Cons: What are the pros and cons of each supplement? How is the supplement unique? For what situations is this supplement best?

1 – Best Overall – MegaFood

  • Price = $22.02
  • # of Servings = 30
  • Price per Serving = .73
  • Product Reviews = 4.8/5 with 44 verified reviews
  • Taste / Absorption = 1 capsule per day with meal
  • Labeled Effect = supports digestive & immune health
  • Food Allergens = very safe
  • Pro’s = 14 probiotic strains in good dosage
  • Con’s = doesn’t contain all b vitamins

About “Probiotic”:

Probiotics are a vital part of stomach health. They help to balance the good and bad bacteria in your gut.

MegaFood’s probiotic supplement contains 14 different strains of beneficial bacteria, which helps support digestive health.

20 billion CFU of probiotics is a good amount too.

The main reason we list MegaFlora as our topic choice is because of the 14 different strains in this product, all from a reputable brand with lots of third party certifications.

If you are new to supplements it’s best to go with an option that has lots of ingredients.

Many supplements contain just one or only a few active ingredients. These are better for people who know specifically what ingredient they want.

Beginners are recommended to take a broader more general approach, and for these reasons this is our top option.

Made by “MegaFood”:


About MegaFood: MegaFood started in 1973 and is a verified B-Corporation, which means they meet higher standards for quality, transparency and sustainability. MegaFood provides tons of science, gives back to the community, and is transparent about their supply chain. According to MetaCritic, MegaFood has a 4.3/5 average rating based on 7,100 reviews.

  • Start = 1973
  • Revenue = $67 million
  • Employees = 200
  • Mission = working toward a world where everyone is truly nourished
  • Third Party Certifications = B Certification, USDA Organic Certification, Non-GMO Project Verified, Vegan, Certified Kosher, 125+ Pesticide Free, Certified Gluten-Free
  • Third Party Reviews = 4.3/5 with 7,100 reviews

2 – Highest Concentration – Physician’s Choice

  • Price = $16.96
  • # of Servings = 30
  • Price per Serving = $0.56
  • Product Reviews = 4.6/5 with 91,433 verified reviews
  • Taste / Absorption = 1 vegetarian capsule
  • Labeled Effect = support the stomach’s digestive environment and supports the natural stomach balance
  • Food Allergens = very safe
  • Pro’s = highest concentration of probiotics with prebiotic herbs too, 10 different strains
  • Con’s = no other vitamins or minerals

About “Probiotics 60 Billion CFU”:

This product has the highest dosage of probiotics.

It also contains prebiotics, which help the probiotics grow good bacteria in your stomach.

Probiotics play an important role in gut health, overall digestive system functioning and even your immune system.

This is one of the most popular, highly rated gut health supplements. #1 in Prebiotic Nutritional Supplements.

Made by “Physician’s Choice”:

About Physician’s Choice: Relatively new to the supplement industry, Physician’s Choice is backed by strong science that is accessible on their website. They sell dietary supplements, including probiotics, biotin and ashwagandha. According to ReviewMeta.com, the average adjusted rating is 3.8 from 2,734 verified reviews.

  • Start = 2017
  • Revenue = $16 million
  • Employees = 81
  • Mission = everyone has access to safe, high-quality supplements that actually work
  • Third Party Certifications = cGMP
  • Third Party Reviews = average adjusted rating is 3.8 from 2,734 reviews

3 – Best Science Research – Care/Of

  • Price = $9
  • # of Servings = 30
  • Price per Serving = $0.33
  • Product Reviews = N/A
  • Taste / Absorption = 1 non-gmo, vegetarian capsule, take with a meal
  • Labeled Effect = gut health and immune support
  • Food Allergens = safe
  • Pro’s = Extensive research for quality probiotic strains
  • Con’s = Need a subscription, but can cancel or modify at anytime

About “Probiotic Blend”:

Care/Of’s Probiotic Blend contains three different strains of probiotic bacteria.

This product contains 8 billion CFUs.    Research on it shows that it supports better gut health and immune system function. 

If you’re looking for a quality probiotic with transparent science and high quality guidelines, Care/Of is a good choice.

Made by “Care/Of”:


About Care/Of: Founded in 2016 in New York City, Care/Of personalizes vitamins and mineral supplementation with thorough, transparent science. According to Influenster.com, Care/Of is rated on average 4.5/5 with 240 reviews.

  • Start = 2016
  • Revenue = $19 million
  • Employees = 100
  • Mission = deliver it to you straight
  • Third Party Certifications = GMP, NSF
  • Third Party Reviews = 4.5/5 with 240 reviews

4 – Best for Artichoke Extract – Superior Labs

  • Price = $24.95
  • # of Servings = 180
  • Price per Serving = $0.14
  • Product Reviews = 4.7/5 with 401 verified reviews
  • Taste / Absorption = 1 vegetarian capsule per serving, have with meal
  • Labeled Effect = promote healthy digestive function
  • Food Allergens = very safe
  • Pro’s = high quality artichoke extract which people commonly use for indigestion, lots of great science
  • Con’s = no vitamins or minerals

About “Artichoke Leaf Extract”:

This is a great supplement that extensive research says has medicinal qualities.

Numerous clinical studies have looked at this ingredient.

Benefits include gut health, lower cholesterol and many other benefits like cardiovascular health.

If you have never tried a supplement for stomach health, and you want something natural, this is a good product to try.

Made by “Superior Labs”:

About Superior Labs: Began in 2007, geared for athletes, and has FDA, GMP certification. Mission statement emphasizes purity, testing, and quality. According to ReviewMeta.com, Superior Labs has an average adjusted rating of 4.3/5 with 3902 verified reviews.

  • Start = 2007
  • Revenue = $6 million
  • Employees = less than 25
  • Mission = purity, testing, and quality
  • Third Party Certifications = NSF, GMP
  • Third Party Reviews = average adjusted rating of 4.3/5 with 3902 reviews

6 – Best for Slippery Elm – Integrative Therapeutics

  • Price = $45.50
  • # of Servings = 50
  • Price per Serving = $0.91
  • Product Reviews = 4.8/5 with 39 verified reviews
  • Taste / Absorption = 2 vegetarian capsules per serving, at beginning of meals
  • Labeled Effect = provide gentle support for digestion
  • Food Allergens = very safe
  • Pro’s = Similase is popular known brand for digestive support
  • Con’s = This product contains slippery elm. Slippery Elm should not be taken together with any medication as it may interfere with absorption

About “Similase Sensitive Stomach”:

A small clinical study found slippery elm improved bowel habits and nutrient absorption in patients with IBS.

Slippery elm contains mucilage, which is considered to have a relaxing effect when applied topically.

However, human data is lacking.

Finally, on labels for supplements it’s rare to see a warning sign to not mix with other medications.  This product has such a warning.  

Most supplements are totally safe so when they do warn you about something heed it!

Made by “Integrative Therapeutics”:

About Integrative Therapeutics: Began in Wisconsin in 2000. Values science, and provides good product descriptions. According to ReviewMeta.com, average adjusted rating is 4.3/5 from 5,303 verified reviews.

  • Start = 2000
  • Revenue = $86 million
  • Employees = 300
  • Mission = support you with every step of your health journey
  • Third Party Certifications = GMP, NSF, Emerson Quality Program
  • Third Party Reviews = average adjusted rating is 4.3/5 from 5,303 verified reviews

7 – Best for Mushrooms – Real Mushrooms

  • Price = $29.95
  • # of Servings = 60
  • Price per Serving = $0.73
  • Product Reviews = 4.9/5 with 57 verified reviews
  • Taste / Absorption = 1 vegetarian capsule per serving, can take on empty stomach
  • Labeled Effect = digestive health
  • Food Allergens = very safe
  • Pro’s = contains more than 8% Beta Glucans
  • Con’s = no vitamins or minerals

About “Organic Siberian Chaga Extract Capsules”:

Chaga mushrooms are known for their high antioxidant levels.

Beta Glucans are also very beneficial. They are the most well-researched ingredient behind the positive effects of mushrooms.

Mushrooms, in general, make for great dietary supplements and can support healthy digestion.

Organic matters because you’re taking it in an uncontaminated form and there are no pesticides or chemicals on it.

This is a high-grade mushroom supplement, and if you’re looking for a mushroom supplement, it’s a good option to try.

Made by “Real Mushrooms”:

About Real Mushrooms: Since its inception in 1989, Nammex has been at the forefront of mushroom extracts’ development and production for the health and wellness sector. Over 1500 practitioners are prescribing Real Mushrooms. Real Mushrooms contain >8% Beta-glucans without added starch, mycelium, or grain of any kind. ReviewMeta.com gives an average adjusted rating of 4.6/5 with 361 reviews.

Author Affiliate Note: I have interviewed Jeff Chilton, founder of Real Mushrooms, take their supplements myself, and am a huge fan.

  • Start = 1989
  • Revenue = less than $5 million
  • Employees = less than 25
  • Mission = deliver the best possible medicinal mushrooms extracts in their purest form, without any carriers or grain fillers
  • Third Party Certifications = Certificates of Analysis available upon request
  • Third Party Reviews = average adjusted rating 4.6/5 from 361 reviews

8 – Best for Pure Ginger – Botanic Choice

  • Price = $5.00
  • # of Servings = 30
  • Price per Serving = $0.16
  • Product Reviews = 4.7/5 with 11 verified reviews
  • Taste / Absorption = 1 gelatin capsule
  • Labeled Effect = relieves occasional stomach upset
  • Food Allergens = safe
  • Pro’s = ginger has been used for many years to treat upset stomach
  • Con’s = For upset stomach (not stomach health)

About “Ginger Root Capsules 550 mg”:

This common herb is beloved around the world for treating occasional indigestion.

This supplement is best if you’re looking for something natural for an upset tummy.

If you want stomach health in general then probiotics are a better bet.

Made by “Botanic Choice”:

botanic choice

About “Botanic Choice”: Botanic Choice started in 1910, over 100 years ago. The company is family owned and has millions of customers worldwide. They are one of the oldest supplement companies still around today. According to MetaCritic, Botanic Choice has a 3.8/5 rating with 1,496 reviews.

  • Start = 112 years old, founded in 1910
  • Revenue = $18 million
  • Employees = 107
  • Mission = dedicated to making effective natural health solutions available to all
  • Third Party Certifications = GMP
  • Third Party Reviews = 3.8/5 with 1,496 reviews

9 – Best for IBS – Super Naturals

  • Price = $24.95
  • # of Servings = 30
  • Price per Serving = $0.83
  • Product Reviews = 4.6/5 with 25 verified reviews
  • Taste / Absorption = 2 vegetarian capsules
  • Labeled Effect = clinical trials and studies on the natural ingredients in this IBS treatment have proven to provide real relief for IBS symptoms
  • Food Allergens = very safe
  • Certifications = Made in USA, GMP
  • Pro’s = many amino acids in highest quantities per serving
  • Con’s = 4 capsules per serving

About “Natural IBSolution”:

Irritable Bowel Syndrome (IBS) is a common digestive condition characterized by cramping, abdominal discomfort, bloating, gas, diarrhea, and constipation that affects the entire large intestine (colon).

Some estimates say inflammatory bowel disease affects at least 1 in 4 persons on the planet.

Good news – Clinical trials and research on the natural components in this IBS supplement have shown that it can help  alleviate digestive tract problems.

Made by “Super Naturals”:

About Super Naturals: Based in Utah, this 9 year old business helps people with poop. They have a fun website with entertaining stories. According to ReviewMeta.com, average adjusted rating is 4.1/5 from 536 verified reviews. 

  • Start = 2012
  • Revenue = less than $5 million
  • Employees = less than 25
  • Mission = help others with this embarrassing and debilitating issue
  • Third Party Certifications = GMP, 
  • Third Party Reviews = average adjusted rating is 4.1/5 from 536 reviews

10 – Best for Zinc – Life Extension

  • Price = $33.00
  • # of Servings = 60
  • Price per Serving = $0.55
  • Product Reviews = 4.5/5 with 31 verified reviews
  • Taste / Absorption = 1 vegetarian capsule, take before bed or in the morning
  • Labeled Effect = protect your stomach lining and promote gastric health
  • Food Allergens = very safe
  • Pro’s = good amino profile, limited science
  • Con’s = warning label says only to take 1 month daily

About “Gastro-Ease”:

Gasto-Ease is a quality supplement with research supporting its active probiotic ingredient.

This supplement also contains a bunch of zinc which can help probiotic growth.

However, there is a label saying copper deficiency may occur if you take it daily for over 1 month.

Made by “Life Extension”:

life extension

About Life Extension: Life Extension began in 1980 and is still going 40 years later. In 2021 ConsumerLab.com voted Life Extension as #1 Rated Catalog/Internet Merchant. According to ReviewMeta.com, Life Extension’s average adjusted rating of 4.1/5 from 24, 224 verified reviews. 

  • Start = 1980
  • Revenue = $168 million
  • Employees = 500
  • Mission = Achieve your goals with the best nutritional products that science can offer
  • Third Party Certifications = GMP, Non-GMO
  • Third Party Reviews = average adjusted rating of 4.1/5 from 24, 224 reviews

11 – Most Familiar – Pepto Bismol

  • Price = $16.49
  • # of Servings = 60
  • Product Reviews = 4.7/5 with 98 verified reviews
  • Taste / Absorption = 2 taste-free softgel capsules
  • Labeled Effect = Prevent occasional nausea & vomiting due to motion or morning sickness
  • Food Allergens = safe
  • Pro’s = ginger and chamomile are well known and familiar, Pepto Bismol also familiar brand
  • Con’s = just herbs no vitamins or minerals

About “Herbal Blends Ginger & Chamomile”:

Pepto-Bismol products have been around for over 100 years.

Pepto-Bismol is best known for their original bismuth subsalicylate formula that has helped people in the past with stomach problems.

However, this Herbal Blends product does not contain any of those ingredients but rather ginger and chamomile herbs that help relieve symptoms like stomach ache.

Made by “Pepto Bismol”:

About Pepto Bismol: Located in Ohio, Pepto Bismol began over 100 years ago! It’s been specializing in digestive issues for a long time. According to ReviewMeta.com, average adjusted rating is 4.3/5 from 2,029 verified reviews.

  • Start = 1900
  • Revenue = $15 million
  • Employees = 80
  • Mission = provide effective relief of multiple stomach symptoms
  • Third Party Certifications
  • Third Party Reviews = average adjusted rating is 4.3/5 from 2,029 reviews

Can supplements improve gut health?

Probiotics are helpful in improving digestion health, and in preventing bloat and discomfort.

Probiotics help to reduce inflammation in the digestive system by preventing the accumulation of bacterial infections. These medications can relieve symptoms of intestinal disorders like IBS, diarrhea and intestinal inflammation.

Harvard Health states “Since the mid-1990s, clinical studies suggest that probiotic therapy can help treat several gastrointestinal ills, delay the development of allergies in children, and treat and prevent vaginal and urinary infections in women”.

As such probiotic supplements can be a role if you aren’t getting enough good bacteria from your diet.


We hope this article helps you make an informed decision before purchasing any digestive supplements.

If you want even more information about what your body needs, you may want to consider a blood test to see if your body is showing signs of inflammation. As stomach issues and inflammation are often related, a blood test for inflammation can provide valuable information.

If you have any questions or comments please let us know.

If we missed one of the other great gut health supplements on the market for stomach health, feel free to also let us know.

Affiliate Disclosure: ​​Some of the links above are affiliate links, meaning that if you decide to purchase a product after clicking one, we may earn a commission. This commission comes at no additional cost to you. 

Medical Disclaimer: This information should not be taken as medical advice. Please consult your doctor before taking any supplements.

About the Author

Jared Levenson is a former binge eating wrestler turned Zen Buddhist Monk, Internal Family Systems counselor and nutrition wellness coach. He's helped hundreds of people through universal meal principles and internal family systems to make peace with food, stop binge eating, and find true health and wholeness.


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