Looking to cleanse your liver and improve your overall health? There are many supplements on the market that claim to help detoxify and support liver function, but which one is right for you?
In this blog post, we will discuss 7 of the best supplements for detoxifying and cleaning your liver.
We’ll also provide tips on how to choose the right liver detox supplement for you and how to use it for optimal liver results. So read on to learn more!
A liver in good condition is essential for your body to function normally. But the liver needs a healthy environment to thrive in and that’s where your actions come in.
If you have a liver condition such as NASH, you can take steps to alleviate the damage. To ensure that you are dealing with this disease, you need to take a nash test liver. After finding out the stage of the diagnosis, you can start with your lifestyle changes.
Please keep in mind supplements are lightly regulated by the FDA. Their stated claims have no guarantee. They aren’t cures or treatments for any diseases.
Food is your best source of nutrition, and lifestyle your most important medicine – especially for liver detoxication! Please check with your doctor before starting any supplement program.
Please note we include items that we trust will be useful to our visitors. If you click one of the links on our site, we may get a commission.
Finally be sure to check out the frequently asked question section below our top picks – let’s dive in!
Best Liver Detox Supplements
Best Overall – Nature’s Craft
Best Blend – Pure Encapsulations
Best for Pure Milk Thistle Extract – Bulk Supplements
Best for Liver Cleanse Detox – Arazo Nutrition
Best for Liver Cleanse Detox – Naturewise
Best Blend Runner-Up – Botanic Choice
Best for D-Mannose – Superior Labs
Best Overall

Price = $20.49
# of Servings = 30
Price per Serving = $0.68
Product Reviews = 4.5/5 (24,117 reviews)
Serving Size = 2 Capsules
Taste / absorption = Unflavored
Labeled Effect = Promote strong functioning live
Food Allergens = Safe
Pros = Amazon #1 Best Seller in Milk Thistle Herbal Supplements, competitive price
Cons = None
About Liver Cleanse Detox & Repair Complex
Liver Cleanse Detox & Repair Complex contains a blend of milk thistle, dandelion root, artichoke, beet root, yarrow, and chicory root.
All these ingredients are all known to promote healthy liver function.
Milk thistle is especially known to nourish and help repair the liver, while also stimulating new liver cell production.
It can also lower cholesterol and improve skin health with its anti-aging properties.
As Amazon #1 Best Seller in Milk Thistle Herbal Supplements, with a competitive price, no wonder this is our top choice.
Made by Nature’s Craft:
According to ReviewMeta.com, Nature Craft’s adjusted average review is 4.3/5 from 15,033 verified reviews.
Start = 2013
Revenue = less than $5 million
Employees = less than 25
Mission = improve your health, improve your life; naturally
Third Party Certifications = GMP
Third Party Reviews = adjusted average review is 4.3/5 from 15,033 verified reviews
Best Blend
https://www.pureformulas.com/livergi-detox-60-vegetarian-capsules-by-pure-encapsulations.html

Price = $31.40
# of Servings = 30
Price per Serving = $1.04
Product Reviews = 4.7/5 (48 reviews)
Serving Size = 2 Capsules
Taste / absorption = Unflavored
Labeled Effect = Support the GI tract and liver
Food Allergens = Safe
Pros = High quality blend of traditional herbal ingredients, great brand company
Cons = Higher price per serving
About Liver-G.I. Detox
Liver-G.I. Detox by Pure Encapsulations gives you a mix of botanicals and nutrients that have been shown to be beneficial for the detoxification process and overall gastrointestinal health.
Liver-G.I. Detox contains ingredients like alpha lipoic acid, milk thistle, and dandelion root extract, all of which have been traditionally used to support liver health.
In addition, this formula also includes ginger root extract and artichoke leaf extract to help soothe the digestive system.
Made By Pure Encapsulations:
Pure Encapsulations began in 2004. According to ReviewMeta.com, Pure Encapsulations has a 4.5/5 average rating from 12,280 reviews. Pure Encapsulations lists over 50 clinical studies going back to 2006 on their website.
Start = 2004
Revenue = $35 million
Employees = 170
Mission = it’s what’s inside that counts
Third Party Certifications = Egg Free, Gluten Free, GMO Free, GMP, Certification Made in the USA, Peanut Free, Wheat Free, Hypoallergenic, NSF
Third Party Reviews = 4.3/5 with 7,100 reviews
Best for Pure Milk Thistle Extract
https://www.bulksupplements.com/products/milk-thistle-extract-powder?_pos=1&_sid=9b4837b62&_ss=r

Price = $17.96
# of Servings = 400
Price per Serving = $0.04
Product Reviews = 4.8/5 (630 reviews)
Serving Size = 250 milligrams
Taste / absorption = Unflavored
Labeled Effect = Supports liver health
Food Allergens = Safe
Pros = Pure Milk Thistle extract, an effective and popular supplement, great price per serving
Cons = No other vitamins, minerals or herbs
About Milk Thistle Extract
Milk Thistle Extract – a pure extract made from the seeds of the milk thistle plant.
This incredible supplement has been used for centuries for its wide range of health benefits, including supporting heart health, managing cholesterol levels, aiding cognitive function, and promoting liver health.
Packed with antioxidants and anti-inflammatory agents, Milk Thistle Extract is a natural way to support your overall health and wellbeing. It’s the most common ingredient found within liver supplements for good reason.
While there are no other vitamins and minerals in Bulk Supplement’s Liver Extract, they offer an extremely competitive price per serving.
Made By Bulk Supplements:
Bulk Supplements started in 2011 and is based in Nevada. Its main manufacturing facility is FDA registered. According to ReviewMeta.com, average adjusted rating is 4.4/5 from 39,370 verified reviews.
Start = 2011
Revenue = $10 million
Employees = 50
Third Party Certifications = NSF, cGMP
Third Party Reviews = 4.4/5 from 39,370 reviews
Best for Liver Cleanse Detox

Price = $19.90
# of Servings = 30
Price per Serving = $0.66
Product Reviews = 4.3/5 (12,135 reviews)
Serving Size = 2 Veggie Capsules
Taste / absorption = Unflavored
Labeled Effect = Promotes strong liver function
Food Allergens = Safe
Pros = Amazon’s Choice for “liver cleanse”, high quality blend of herbs
Cons = None
About Liver Cleanse Detox
Liver Cleanse Detox contains natural botanicals and multiple plant herbs that promote strong liver function. Such herbs include milk thistle extract, choline, dandelion root, alfalfa, celery seed, burdock root, yellow dock, grape seed extract, turmeric, red raspberry, berberine, ginger and more.
Milk thistle extract is the main ingredient in Liver Cleanse Detox and supports production of new liver cells, repair and nourish damaged livers, supports hangovers and cholesterol levels.
Listed Amazon’s Choice for “liver cleanse” with a decent price point from a solid brand.
Made By ARAZO Nutrition:
Began in 2012 and located in Delaware. Emphasizes Non-GMO and quality. According to ReviewMeta.com, Arazo Nutrition gets a 4.2/5 average adjusted rating from 2,134 verified reviews.
Start = 2012
Revenue = less than $5 million
Employees = less than $25
Mission = bring good health and a good life to everyone who desires to live better and live healthier
Third Party Certifications = GMP, Non-GMO
Third Party Reviews = 4.2/5 average adjusted rating from 2,134 verified reviews
Best Herbal Blend
https://www.naturewise.com/products/liver-balance-complete

Price = $29.99
# of Servings = 60
Price per Serving = $0.49
Product Reviews = 4.7/5 (58 reviews)
Serving Size = 2 Vegetarian Capsules
Taste / absorption = Unflavored
Labeled Effect = Promote strong liver function
Food Allergens = Safe
Pros = High quality herbal blend, competitive pricing
Cons = Similar to other products
About Liver Balance Complete
Liver Balance Complete encourages natural detoxification, strengthening of liver function, and reduced stress.
The formula features three blends of clinically studied botanical ingredients to lighten the toxic load, promote healthy liver function, and defend against damage.
With artichoke, dandelion, milk thistle, picrorhiza kerria, rishi mushroom, turmeric, and more, Liver Balance Complete is another liver solution for optimal liver health.
While similar to Liver Cleanse Detox featured above, the nutrients listed here are different with more of an Asian / Chinese emphasis.
In comparison to Liver Cleanse Detox, Nature wise is a more established company and offers a better price per serving.
Made by Naturewise:
Founded in 2012 in California, Naturewise aims to promote health and inspire wellbeing. According to ReviewMeta.com, Naturewise has a 4.2/5 average adjusted rating from 32,542 verified reviews.
Start = 2012
Revenue = $31 million
Employees = less than 25
Mission = promote health and inspire wellbeing
Third Party Certifications = Manufactured in US,
Third Party Reviews = 4.2/5 average rating from 32,542 reviews
Best Blend Runner-Up
https://www.botanicchoice.com/Liver-Gall-Bladder/Liver-10-Complex-60-Capsules.axd

Price = $24.00
# of Servings = 30
Price per Serving = $0.80
Product Reviews = 4.2/5 (13 reviews)
Serving Size = 2 veggie capsules
Taste / absorption = Unflavored
Labeled Effect = Supplies ingredients studied for liver health with promising results
Food Allergens = Soy
Pros = High quality blend of effective nutrients
Cons = Fewer reviews
About Liver 10 Complex
Liver 10 Complex is a great formula delivering the most recommended liver herbs, milk thistle, and supplies other ingredients studied for liver health with promising results.
For example, Liver 10 Complex includes an adaptogen that is recognized in the Chinese, Japanese, South Korean and Russian pharmacopeias for liver health. It also contains a component popular in the Amazon for a variety of health reasons, including liver health and chronic liver disease.
While this supplement doesn’t have as many reviews, the stellar blend of ingredients is worthwhile.
Made By Botanic Choice:
Botanic Choice started in 1910, over 100 years ago. The company is family owned and has millions of customers worldwide. They are one of the oldest supplement companies still around today. According to MetaCritic, Botanic Choice has a 3.8/5 rating with 1,496 reviews.
Start = 112 years old, founded in 1910
Revenue = $18 million
Employees = 107
Mission = dedicated to making effective natural health solutions available to all
Third Party Certifications = GMP
Third Party Reviews = 3.8/5 with 1,496 reviews
Best for D-Mannose – Superior Lab
https://superiorlabs.com/products/d-mannose

Price = $22.95
# of Servings = 120
Price per Serving = $0.19
Product Reviews = 4.8/5 (1077 reviews)
Serving Size = 1 Vegetarian Capsule
Taste / absorption = Unflavored
Labeled Effect = Support optimum liver function
Food Allergens = Safe
Pros = Pure D-Mannose, highly competitive pricing
Cons = None
About D-Mannose
D-Mannose was first discovered in 1921 as a by-product of ivory nut shavings used to make buttons. In 1998, D-Mannose were utilized to help people who were thought to have glycosylation deficiency.
This led to the discovery of D-Mannose’s usefulness in treating bacterial infections, notably urinary tract infections (UTIs).
Since then, D-Mannose has been proven to aid in the maintenance of urinary tract health and combat several bacteria.
Additionally, D-Mannose can support optimum liver function and encourage intestinal health.
Made By Superior Labs:
Began in 2007, geared for athletes, and has FDA and GMP certification. Mission statement emphasizes purity, testing, and quality. According to ReviewMeta.com, Superior Labs has an average adjusted rating of 4.3/5 with 3,902 verified reviews.
Start = 2007
Revenue = $6 million
Employees = less than 25
Mission = purity, testing, and quality
Third Party Certifications = NSF, GMP
Third Party Reviews = average adjusted rating of 4.3/5 with 3902 reviews
Who benefits most from liver supplements?
When it comes to liver supplements, anyone with liver struggles or concerns may benefit from them. However, there are certain groups of people who may benefit more from taking liver supplements. These groups include:
People with liver disease
People with nonalcoholic fatty liver disease
People with alcohol addiction
People exposed to toxins
Smokers
If you fall into any of these categories, then you may want to consider taking one of the best liver detox supplements we’ve listed above or where you’ve found elsewhere after researching.
Liver supplements can help improve your overall health and well-being. So if you are looking for a way to improve your health, then consider taking a liver supplement.
Risks
Side effects are rare but can include:
Allergic reactions
Digestive issues
Nausea
Headaches
Dizziness
If you have any concerns about taking liver supplements, then please speak with your doctor before doing so.
Otherwise, liver supplements are generally safe for most people to take.
How to improve liver health naturally
By far and away the best thing you can do for your liver is to stop or decrease drinking alcohol.
Here are some other tips to care for your liver:
eat a healthy diet that includes plenty of fruits, vegetables, and whole grains
Also, be sure to get enough protein
And avoid processed foods, sugary drinks, and excessive amounts of saturated and trans fats.
Finally, exercise regularly to help keep your liver functioning properly.
You should also test your blood. There are a variety of blood tests available. Read our top blood test reviews here.
How soon after taking liver supplements will I feel better?
But how soon after taking the supplement will you start to feel better?
It depends on the person. Some people may notice a difference within a few days or weeks, while others may not see any improvement for months. It also depends on the severity of your liver damage and how well you stick
Best Supplement to Detox Liver – Summary
So if you are looking for a way to improve your health, then consider taking a liver supplement.
Remember that not everyone will benefit from them and side effects are rare but can include allergic reactions, digestive issues, nausea, headaches, and dizziness.
Speak with your doctor before taking liver detox supplements if you have any concerns.
What liver detox supplements are your favorite? Let us know in the comments!
One final note – be sure to check out our complete database of supplement reviews so you can find the best supplement for your personal situation!
If you are not sure how to research supplements to conduct your own review, read our ultimate beginner’s guide to supplements and vitamins here.