8 Best Supplements for CoQ10

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Do you know what CoQ10 is? It’s a vitamin-like substance that is found in every cell of the body.

CoQ10 is responsible for producing energy in the body, and it declines as we age.

That’s why many people take supplements to increase their CoQ10 levels.

In this blog post, we will discuss 8 of the best supplements for CoQ10. We’ll also talk about the benefits of taking these supplements and how they can help improve your health!

Keep in mind supplements are lightly regulated by the FDA. Their stated claims have no guarantee. They aren’t cures or treatments for any diseases.

Please check with your doctor before starting any supplement program and that we include items that we trust will be useful to our visitors. If you click one of the links on our site, we may get a commission. If you have questions see the FAQ section below – now let’s dive in!

Best Overall – Ultra CoQ10

  • Price = $28.00
  • # of Servings = 120
  • Price per Serving = $0.23
  • Product Reviews = 4.7/5 (48,942 reviews)
  • Serving Size = 1 Softgel
  • Taste / absorption = Unflavored
  • Labeled Effect = Heart health support
  • Food Allergens = Soy
  • Pros = #1 Amazon Best Seller in CoQ10 Nutritional Supplements
  • Cons = No other vitamins, minerals or herbs (besides Vitamin E)

About Ultra CoQ10

Look no further than Qunol Ultra CoQ10. This top-of-the-line supplement has been clinically shown to absorb 3X better than regular CoQ10, so you can reap the maximum benefits of this important nutrient.

Since CoQ10 is vital for cell energy production, taking Qunol Ultra can help support a healthy heart and vascular system. It can also help maintain cognitive function and healthy brain cells, making it an excellent choice for those wanting to prevent cognitive decline as they age. And because Qunol Ultra is 100% water and fat soluble, its AbsorbFast technology ensures that your body can make the most of every dose via it’s superior absorption.

As the #1 Amazon Best Seller in CoQ10 Nutritional Supplements, this is one of the best bets if you’re looking for the best CoQ10 supplement.

Made by Qunol:

When it comes to supplements, it’s not what you take; it’s what you absorb that matters. According to ReviewMeta.com, Qunol has a 4.4/5 average adjusted rating with 82 verified reviews

A Close 2nd – High Absorption CoQ10

  • Price = $19.98
  • # of Servings = 120
  • Price per Serving = $0.16
  • Product Reviews = 4.6/5 (25,514 reviews)
  • Serving Size = 1 Softgel
  • Taste / absorption = Unflavored
  • Labeled Effect = Enhance vitality across many body systems
  • Food Allergens = Safe
  • Pros = High quality CoQ10 with black pepper
  • Cons = No other vitamins, minerals or herbs

About High Absorption CoQ10:

Doctor’s Best has designed a natural black pepper extract that will help you quickly and efficiently restore your stores of CoQ10 because CoQ10 taken with BioPerine enhancer ensures maximum absorption of the nutrients.

Made by Doctor’s Best:

Founded by a physician in 1990. According to ReviewMeta.com, Doctor’s Best has a 4.1/5 average adjusted rating with 7,803 verified reviews.

3rd Best If You Like Good, Cheap, Powder – Coenzyme CoQ10

  • Price = $19.96
  • # of Servings = 100
  • Price per Serving = $0.19
  • Product Reviews = 4.7/5 (1,076 reviews)
  • Serving Size = 1 Softgel
  • Taste / absorption = Unflavored
  • Labeled Effect = Supports the cardiovascular & heart health
  • Food Allergens = Soy
  • Pros = Pure CoQ10, competitive pricing
  • Cons = No other vitamins, minerals or herbs

About Coenzyme Q10 (CoQ10):

Pure, oxidized reduced form of CoQ10 powder is made from a reputable company at a competitive price. If you are looking for a pure CoQ10 powder dietary supplement this is a good choice.

Made by Bulk Supplements:

Bulk Supplements started in 2011 and is based in Nevada. According to ReviewMeta.com, Bulk Supplement’s average adjusted rating is 4.4/5 from 39,370 verified reviews.

4th Best For It’s Great Ingredients – CoQ-10 Power Plex

  • Price = $22.00
  • # of Servings = 30
  • Price per Serving = $0.73
  • Product Reviews = 4.9/5 (17 reviews)
  • Serving Size = 1 Capsule
  • Taste / absorption = Unflavored
  • Labeled Effect = Supports the energy activity of the heart.
  • Food Allergens = Safe
  • Pros = High quality blend of ingredients including CoQ10
  • Cons = Fewer reviews

About CoQ-10 Power Plex

If you’re looking for the most comprehensive CoQ-10 formula available, look no further than Botanic Choice’s CoQ-10 Power Plex. This powerful supplement includes six ingredients for heart, brain, and total health support. With its potent antioxidants, this easy-to-swallow daily capsule can help fight the effects of poor diet, inactivity, and aging. And with the addition of Acetyl L-Carnitine, CoQ-10 Power Plex provides cognitive support as well. Plus, with vitamins C, E, B-12, and folic acid, this supplement offers total health protection. While this supplement has fewer reviews, it makes up for it with the blend of ingredients.

Made By Botanic Choice:

Botanic Choice started in 1910, over 100 years ago. The company is family owned and has millions of customers worldwide. They are one of the oldest supplement companies still around today. According to MetaCritic, Botanic Choice has a 3.8/5 rating with 1,496 reviews.

5th Best If You Like Lots of Certifications – CoQ10 Alpha Lipolic Acid+

  • Price = $26.99
  • # of Servings = 30
  • Price per Serving = $0.89
  • Product Reviews = 5.0/5 (18 reviews)
  • Serving Size = 2 Capsules
  • Taste / absorption = Unflavored
  • Labeled Effect = Supports cardiovascular health
  • Food Allergens = Safe
  • Pros = Company has many quality certifications
  • Cons = Fewer reviews

About Nature’s Lab CoQ10

This supplement provides three key nutrients that are necessary for energy production in all cells of the body. Coenzyme Q10 is an important antioxidant that helps protect cells from damage, while alpha lipoic acid and acetyl-L-carnitine hcl work together to support cellular energy production. While this supplement has fewer reviews, the company producing is one of the most highly certified company’s we’ve reviewed.

Nature’s Lab is FDA, GMP, Non-GMO, USDA Organic, How 2 Recycle, Made in USA, Kosher, Halal, Cruelty Free certified, so you can be sure you’re getting a high quality product.

Made by Nature’s Lab:

Started in 2011 in Las Vegas by Wayne Gorsek, founder of Vitacost in 1994. According to Reviews.io, the company has a 4.9/5 rating with 656 reviews.

6th Best For Purity – CoQ10

  • Price = $19.95
  • # of Servings = 60
  • Price per Serving = $0.33
  • Product Reviews = 4.5/5 (59 reviews)
  • Serving Size = 1 Vegetarian capsule
  • Taste / absorption = Unflavored
  • Labeled Effect = Supports healthy cardiovascular health
  • Food Allergens = Safe
  • Pros = High quality CoQ10 with black pepper
  • Cons = Similar to other products on market (see Doctor’s Best)

About CoQ10

This CoQ10 supplement is formulated with MCT oil and BioPerine to increase absorption and bioavailability. So you can be sure you’re getting the most out of each dose. However, the BioPerine and CoQ10 is a popular combination.

Made by Superior Labs:

Began in 2007, geared for athletes, and has FDA, GMP certification. Mission statement emphasizes purity, testing, and quality. According to ReviewMeta.com, Superior Labs has an average adjusted rating of 4.3/5 with 3,902 verified reviews.

7th Best For “Proprietary” Ingredient – Super Ubiquinol CoQ10

  • Price = $47.25
  • # of Servings = 60
  • Price per Serving = $0.78
  • Product Reviews = 4.9/5 (456 reviews)
  • Serving Size = 1 Softgel
  • Taste / absorption = Unflavored
  • Labeled Effect = Provides powerful cardiovascular & antioxidant support
  • Food Allergens = Safe
  • Pros = Proprietary formula
  • Cons = No other vitamins, herbs or minerals, similar to other supplements on the market

About Super Ubiquinol CoQ10

This unique formula features ultra-absorbable ubiquinol CoQ10 combined with shilajit, an adaptogen that has been shown in preclinical models to promote mitochondrial energy production.

CoQ10 is essential for cellular energy production, and Super Ubiquinol CoQ10 is formulated with a highly bioavailable form of CoQ10 to ensure superior absorption and effectiveness.

If you’re looking for an CoQ10 supplement that is highly bioavailable, Super Ubiquinol CoQ10 is another great choice.

Made by Life Extension:

Life Extension began in 1980 and is still going 40 years later. In 2021 ConsumerLab.com voted Life Extension as #1 Rated Catalog/Internet Merchant. According to ReviewMeta.com, Life Extension’s average adjusted rating of 4.1/5 from 24, 224 verified reviews. 

8th Best If You Love Red Yeast Rice – Red Yeast Rice

  • Price = $20.33
  • # of Servings = 60
  • Price per Serving = $0.33
  • Product Reviews = 4.7/5 (64 reviews)
  • Serving Size = 2 Capsules
  • Taste / absorption = Unflavored
  • Labeled Effect = Cardiovascular support
  • Food Allergens = Safe
  • Pros = High quality CoQ10 supplement, made by very well known brand
  • Cons = No other vitamins, minerals or herbs (besides red yeast rice)

About Red Yeast Rice 1200 mg

Red yeast rice is a type of fermentation extract made from rice that originates from China, Japan, and other Asian countries. Some studies suggest that red yeast rice may help to regulate both circulatory and cardiovascular health. In fact, some studies have suggested that red yeast rice may be able to lower LDLs (Low Density Lipids, also known as “bad” cholesterol) while improving HDLs (High Density Lipids, also known as “good” cholesterol).

Now, PureFormulas’ red yeast rice is combined with another beneficial ingredient called CoQ10. Also known as Coenzyme Q10, this ingredient supports nearly every cell in the body and is essential for energy production. This powerful combination makes PureFormulas’ Red Yeast Rice with CoQ10 a potent supplement for supporting circulatory and cardiovascular health while boosting energy levels.

Made by Pure Formulas:

Founded in 2007 in Florida, Pure Formulas has over 600,000 active customers. Newsweek recently named Pure Formulas the “#1 Health E-Tailer” for 2022. According to Trustpilot, Pure Formulas has 65,276 verified reviews with an average rating of 4.6/5. 

What are CoQ10 Supplements?

Coenzyme Q10, or CoQ10, is a naturally occurring compound found in the human body. It plays a role in cellular energy production and acts as an antioxidant. As we age, our natural levels of CoQ10 tend to decrease. Supplementing with CoQ10 has been scientifically shown to have potential benefits for cardiovascular health and may also improve symptoms of conditions like migraines and gum disease.

However, it is important to consult with your healthcare provider before starting any new supplement, as CoQ10 can interact with certain medications and may not be appropriate for everyone. Overall, CoQ10 can be a helpful addition to a healthy lifestyle but should be used under the guidance of a healthcare professional.

CoQ10 Best Supplement – What factors do we use to rank?

1 – Price: What’s the price of the supplement? What’s the cost per serving? At Eating Enlightenment we value quality over price. However, all else being equal, then price comes into consideration. 

2 – Reviews: How many reviews for each product? What’s the average rating? How many third party reviews? We strongly believe in third party reviews. Many supplement companies list positive reviews on their website, but third party reviews include negative comments. We always go with third party reviews.

3 – Reputation: How reputable is the brand behind the supplement? How long has the brand been around? What’s their mission? We believe that a company’s intention is highly important and should be one of your top purchasing decision factors. See the top 21 most popular supplement manufacturers.

4 – Taste / Absorption = What’s the taste? How quickly does your body absorb the supplement? Do reviews mention any negative side effects like an upset stomach?

5 – Perceived Therapeutic Effect = What beneficial effects or feelings does this supplement promote? Learn if you are taking too many supplements.

6 – Food Allergens = Does the company provide allergen info?

7 – Science / Certifications: Does the company list transparent scientific studies on their website? Do third party certifications test the company’s supplement for quality control? How many certifications does the company have? Read here for more info about whether supplements are FDA approved.

8 – Pros/Cons: What are the pros and cons of each supplement? How is the supplement unique? For what situations is this supplement best?

Why are CoQ10 supplements important? 

Coenzyme Q10, also known as CoQ10, is a crucial component of cellular energy production. It’s found in every cell of the body, and particularly abundant in organs like the heart that require a lot of energy.

Unfortunately, our natural levels of CoQ10 decline with age, and certain medications can also deplete it. This can lead to an increased risk for cardiovascular disease and other conditions related to low energy production at a cellular level.

Supplementing with CoQ10 can help to restore these levels and support overall cardiovascular health. In fact, studies have shown that CoQ10 may improve symptoms related to congestive heart failure and high blood pressure. Additionally, it has been shown to improve muscle function in people with certain disorders like muscular dystrophy. If you have any concerns about your CoQ10 levels, talk to your doctor about whether supplementation is right for you.

You may also want to check out 10 Best Supplements for Heart Health.

Who will benefit by taking CoQ10 supplements? 

Individuals with heart disease or high blood pressure may benefit from taking CoQ10 supplements, as they have been shown to improve symptoms and reduce the need for medication. People undergoing treatment for cancer may also see positive effects, as CoQ10 can help to protect healthy cells while undergoing chemotherapy or radiation therapy. In addition, those with neurological disorders like Parkinson’s disease may experience improvement in symptoms with CoQ10 supplementation. Overall, supplementing with CoQ10 offers many potential benefits and should be discussed with your healthcare provider to determine if it is right for you.

Who should not take CoQ10 supplements?

While CoQ10 dietary supplements can provide numerous health benefits, they may not be suitable for everyone. Those who are currently taking blood thinners or cholesterol-lowering medications should talk to their doctor before taking CoQ10, as it can interact with these drugs and increase the risk of bleeding. Pregnant or breastfeeding women should also avoid these supplements, as there is not enough research on its safety during these times. In addition, individuals with diabetes should exercise caution when taking CoQ10, as it may affect blood sugar levels. As always, it’s best to consult with a healthcare professional before starting any new supplement routine.

What are the risks to taking CoQ10 supplements?

Despite being promoted as a miracle supplement for everything from heart disease to migraines, CoQ10 is not without its risks.

Firstly, it can interact with certain medications, including blood thinners and diabetes medications. It may also cause side effects such as stomach upset, nausea, and headaches.

In addition, there is limited research on the long-term effects of taking CoQ10 supplements, and the FDA does not regulate the production or labeling of these supplements. So before starting a regimen of CoQ10 supplements, it’s important to consult with your healthcare provider to weigh the potential benefits against the possible risks.

What time should I take CoQ10 supplements? 

The best time to take CoQ10 supplements is with a meal, preferably one that includes fatty foods. This helps with absorption and allows the CoQ10 to be distributed throughout the body more effectively. Some people prefer to take their supplement in the morning, others in the evening. Ultimately, it is important to determine what works best for you and stick with that schedule consistently. It may also be beneficial to take your supplement at different times on different days, as CoQ10 levels naturally fluctuate throughout the day. However, it’s important to note that high doses of CoQ10 can cause digestive upset if taken on an empty stomach, so it’s best to err on the side of caution and always take your supplement with food.

Food sources for CoQ10

Patients with CoQ10 deficiencies may struggle to find the necessary levels of this important antioxidant in their food. While animal sources, such as meat and organ meats, tend to have higher levels of CoQ10, vegetarians and vegans can still meet their needs through plant-based options. Some good sources include spinach, broccoli, peanuts, and soybeans.

Other foods, such as eggs and poultry also contain CoQ10, but at lower levels than that found in red meat. It’s important for CoQ10 deficient individuals to consult with a dietician or nutritionist to ensure they are receiving the proper amount through their daily food intake, especially if they follow a vegetarian diet. Supplements may be necessary in some cases to meet recommended levels of CoQ10.

Overall, a balanced diet including a variety of whole foods is the best way for CoQ10 deficient patients to obtain this crucial nutrient.

If you want a specific meal plan you may want to order an online blood test for vitamin deficiencies to see if there are nutrient gaps in your diet.

How can I improve my CoQ10 naturally without supplements? 

As we age, our natural CoQ10 levels may begin to decrease, but there are steps we can take to improve them without resorting to supplements. First, adding CoQ10-rich foods into your diet can help boost levels.

These include salmon, sardines, beef, spinach, and broccoli. Regular exercise has also been shown to increase CoQ10 levels in the body. In addition, maintaining a healthy weight and managing conditions like high blood pressure can improve overall CoQ10 levels as well as support heart health. By incorporating these lifestyle changes, you can boost your CoQ10 levels naturally.

How soon after taking CoQ10 supplements will I feel better?

The effects of CoQ10 supplementation can vary greatly from person to person. Some individuals may begin to feel an improvement in their cardiovascular system within a few days, while for others it may take weeks or even longer before they notice a difference.

It is also important to keep in mind that CoQ10 works gradually over time and the benefits may not be immediately apparent. It is recommended to continue taking the supplement consistently for at least 3-6 months before evaluating its effectiveness.

If you do not see any improvement in your symptoms during this time, it would be wise to consult with your healthcare provider to discuss other nutritional products.

If you are looking to start supplementing but aren’t sure where to begin, check out “What Supplements Should I Be Taking? Here Are Top 20”.

If you want to learn more about supplements and vitamins in general, read our Supplements and Vitamins – Ultimate Beginner’s Guide.

About the Author

Jared Levenson is a former binge eating wrestler turned Zen Buddhist Monk, Internal Family Systems counselor and nutrition wellness coach. He's helped hundreds of people through universal meal principles and internal family systems to make peace with food, stop binge eating, and find true health and wholeness.


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